Protein Info for Shew_0662 in Shewanella loihica PV-4

Annotation: NAD(P) transhydrogenase, beta subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 33 to 50 (18 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 113 to 138 (26 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 209 to 228 (20 residues), see Phobius details amino acids 234 to 253 (20 residues), see Phobius details PF02233: PNTB" amino acids 8 to 454 (447 residues), 618.9 bits, see alignment E=3.3e-190

Best Hits

Swiss-Prot: 50% identical to PNTB_RHORU: NAD(P) transhydrogenase subunit beta (pntB) from Rhodospirillum rubrum

KEGG orthology group: K00325, NAD(P) transhydrogenase subunit beta [EC: 1.6.1.2] (inferred from 100% identity to slo:Shew_0662)

Predicted SEED Role

"NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)" in subsystem Phosphate metabolism (EC 1.6.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.1.2

Use Curated BLAST to search for 1.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAN6 at UniProt or InterPro

Protein Sequence (460 amino acids)

>Shew_0662 NAD(P) transhydrogenase, beta subunit (RefSeq) (Shewanella loihica PV-4)
MSMTIIYLAYLVAASLFILGIKGLTKPRTAVRGNQLSALGMFIAVVVTLLDKSILSYEWI
IAGILLGGAIGAVMATKIQVTAMPQMVALLNGFGGGASLFIALASFLDPDSATHVVALIS
IGLTVLIGSVTLSGSFVAFAKLQELISGNPIRVPGNKFINASLLIAALVLTVAVVTTPSN
PTFIYALVAVSLLLGLFLVVPIGGADMPVVIALLNSYSGIAAATTGFITGNTVLIVSGSL
VGASGIILTQIMCKAMNRSLFNVLFGVMAEGGETVDADEVYAGKVTSSSPEEVAMLLETA
ERVVIVPGYGLAMAQAQHAVRELASVLEARGAQVLYAIHPVAGRMPGHMNVLLAEAEVPY
EQLIEMDEINPQFEQTDVAIVIGANDVTNPMAREDKGSPIYGMPILNVDKARTVVVVKRS
LSPGFAGLPNPLFAKDNALMLFGDGKKAIVDLTQSLKEAD