Protein Info for Shew_0640 in Shewanella loihica PV-4

Annotation: TPR repeat-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 160 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF13432: TPR_16" amino acids 41 to 98 (58 residues), 34.9 bits, see alignment E=8.9e-12 PF14559: TPR_19" amino acids 51 to 105 (55 residues), 25.8 bits, see alignment E=5.6e-09 PF13431: TPR_17" amino acids 57 to 89 (33 residues), 24.6 bits, see alignment 1e-08 amino acids 91 to 130 (40 residues), 23.2 bits, see alignment E=2.9e-08 PF00515: TPR_1" amino acids 69 to 102 (34 residues), 40.4 bits, see alignment 8.3e-14 PF13181: TPR_8" amino acids 69 to 102 (34 residues), 38.9 bits, see alignment 2.4e-13 PF07719: TPR_2" amino acids 69 to 102 (34 residues), 34.4 bits, see alignment 6.8e-12 PF13174: TPR_6" amino acids 71 to 101 (31 residues), 21.4 bits, see alignment 1.5e-07 PF13176: TPR_7" amino acids 71 to 103 (33 residues), 25.2 bits, see alignment 6.1e-09 PF13428: TPR_14" amino acids 71 to 110 (40 residues), 29 bits, see alignment E=5.4e-10 PF13414: TPR_11" amino acids 76 to 116 (41 residues), 38.4 bits, see alignment E=3.9e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0640)

Predicted SEED Role

"TPR domain protein, putative component of TonB system" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAL4 at UniProt or InterPro

Protein Sequence (160 amino acids)

>Shew_0640 TPR repeat-containing protein (RefSeq) (Shewanella loihica PV-4)
MGKLIRLSLFVAVTALLGACSTTPQKPEHKGNEQIMAIQSQAEHAYKLAMLDQAESLYLE
VLKSVPNYAPAWFRLGNIYTRTNRHEAAIAAYRRCIELEPNNQKAWYNMGLVRIKQSTNA
LNTASNQGDADSAVGRQIKALLDALNQLQSQPQTTAQAGL