Protein Info for Shew_0579 in Shewanella loihica PV-4

Annotation: arginine N-succinyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF04958: AstA" amino acids 1 to 337 (337 residues), 456.5 bits, see alignment E=2.1e-141 TIGR03244: arginine N-succinyltransferase" amino acids 3 to 338 (336 residues), 450.9 bits, see alignment E=2.2e-139 TIGR03243: arginine and ornithine succinyltransferase subunits" amino acids 3 to 338 (336 residues), 437 bits, see alignment E=3.9e-135

Best Hits

Swiss-Prot: 46% identical to ASTG_PSEAE: Arginine N-succinyltransferase subunit beta (aruG) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00673, arginine N-succinyltransferase [EC: 2.3.1.109] (inferred from 100% identity to slo:Shew_0579)

MetaCyc: 46% identical to arginine succinyltransferase beta subunit (Pseudomonas aeruginosa)
Arginine N-succinyltransferase. [EC: 2.3.1.109]; 2.3.1.109 [EC: 2.3.1.109]

Predicted SEED Role

"Arginine N-succinyltransferase (EC 2.3.1.109)" in subsystem Arginine and Ornithine Degradation (EC 2.3.1.109)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.109

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAF3 at UniProt or InterPro

Protein Sequence (339 amino acids)

>Shew_0579 arginine N-succinyltransferase (RefSeq) (Shewanella loihica PV-4)
MLIIRPIRSSDFDALYQIAIESGHGFTSLPVNEELLRNKIARVEASFVKEIEKPFDEGYL
MVLEDTETGEVVGTCGLEAAVGMVDAFYHYRLGTEVYYSEQIDVRNEVETLTLCHDYTGA
AELCTLFLRDTYRKNNNGRMLSRSRFLFLAQHAERFGDTVIAEMRGESDAEGNSPFYGWL
QKNFLGIDFVQADYLSGLGQKAFMAEMMPKNSVYVCLLPEEAQKVIGEVHTNTRPALNLL
QAEGFRCRGYVDIFDGGPTVECNLNDIRSVRESRLLTVKVGEMPVSSSSFIISNTLLAGY
RATSANLMVSDETDEVILSPELAGALLVAEGEQIRVLAM