Protein Info for Shew_0398 in Shewanella loihica PV-4

Annotation: MSHA pilin protein MshC (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details PF07963: N_methyl" amino acids 1 to 27 (27 residues), 30.4 bits, see alignment 1e-11 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 4 to 27 (24 residues), 23 bits, see alignment 2.5e-09

Best Hits

KEGG orthology group: K10926, MSHA pilin protein MshC (inferred from 100% identity to slo:Shew_0398)

Predicted SEED Role

"MSHA pilin protein MshC" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9X2 at UniProt or InterPro

Protein Sequence (149 amino acids)

>Shew_0398 MSHA pilin protein MshC (RefSeq) (Shewanella loihica PV-4)
MNKQQGFTLVELVTSIILIAILSVVVLPRFFTASSYSAYTLRDELISELRRVQLMALNNL
DRCYKVSVTATSYRADIFGADCNSLTVTGNAQSLPRQTSLSLGGLNSFTLTFDRDGRVTG
SCATGCTIKVAADETLDLSIESQGYIHGR