Protein Info for Shew_0384 in Shewanella loihica PV-4

Annotation: regulatory protein CsrD (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details PF00990: GGDEF" amino acids 223 to 376 (154 residues), 36.9 bits, see alignment E=3.1e-13 PF00563: EAL" amino acids 402 to 632 (231 residues), 156.3 bits, see alignment E=8.7e-50

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0384)

Predicted SEED Role

"MSHA biogenesis protein MshH" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9V8 at UniProt or InterPro

Protein Sequence (636 amino acids)

>Shew_0384 regulatory protein CsrD (RefSeq) (Shewanella loihica PV-4)
MKLTQLLTKKLTGFWLLSLAAVAFIFLLTALVSFIQLTYKFQQQQMTELEEMLLQHQVRH
ELQHLDIWLPQILAAYDAQKFTLIRGDETLYRFDRGNHDQSVVNYDRVLNETLDLHFHIS
LPQPFLLHNISWHGGLVFLVGCIAVGLLVRRGYLWLALQLQGIEDLAKRSHLILSGDYDK
ALAETGHGRPRLINRALTQMLLELDDAQKQRARFDQFIRSNTFLDPESGIGNRLFLKNRL
DALSNKDGMMAPGVLLLLEMEDLDLLQQEADEFSIQELLTQTIGGISHLLDSQANSIFSR
RSYNQFAIVVPQISLADAEKLAARLLKVCLSQPLEGVNNRDDFFHIGVAYFKVGESKEQL
IEEAEMALRAAQFQGNSGWFMYDKGAVDEEFARGSVRWRSFLEYALVNKRVVPFTQAILD
SDGKEHHSEVSCRLRDSSDNLVRATLFLPMAIKCGLIPQIERQVIEAVLFDLLPKSPKDQ
RKYSINLSLDTLTSRAFIRWLQTTLLEYRHLTPRLIFEINEDILVNNLAKLKAPLDMIAK
MGASLCVDRVGQQVVSTQYLQSCRVDLIKLHRSIVRQIHLRQENQLFVRSLIGGLYRTEV
QVFAEGVESLEEWQTLKILGVSAGQGSFFSDPLEAA