Protein Info for Shew_0255 in Shewanella loihica PV-4

Annotation: ion transport 2 domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 transmembrane" amino acids 16 to 37 (22 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 69 to 87 (19 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 126 to 147 (22 residues), see Phobius details amino acids 167 to 184 (18 residues), see Phobius details amino acids 196 to 217 (22 residues), see Phobius details PF07885: Ion_trans_2" amino acids 134 to 217 (84 residues), 58.8 bits, see alignment E=2.1e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0255)

Predicted SEED Role

"Potassium channel protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9H9 at UniProt or InterPro

Protein Sequence (226 amino acids)

>Shew_0255 ion transport 2 domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MNLDKALSNISEKNNFIYLTLALIMLLIAAALVQLLQDNVIEYVIQGIMVVIFIVCFVSL
RFDRKWTHFLRGLAVVWIAAIAAKHLFHIKEMSILMLSLTFVFFYGTFQSLVRKILFSGQ
IDTNKLIGSVALFLLLGLMWAVAYLLLLELDPFAFRGLEAIPWEDNFSNSAYFSFVTLTT
LGYGDISPVTPIAKTLVYLESVVGVFYMAVVVSSLVSSNLGRNAAR