Protein Info for Shew_0242 in Shewanella loihica PV-4

Annotation: molydopterin dinucleotide-binding region (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04879: Molybdop_Fe4S4
  • amino acids 52 to 100 (49 residues), 24.9 bits, 2.4e-09
• PF00384: Molybdopterin
  • amino acids 104 to 520 (417 residues), 119.4 bits, E=2.8e-38
• PF01568: Molydop_binding
  • amino acids 620 to 730 (111 residues), 71.1 bits, E=1.2e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0242)

Predicted SEED Role

"Anaerobic dehydrogenases, typically selenocysteine-containing" in subsystem Anaerobic respiratory reductases

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (5/15 steps found)
• purine nucleobases degradation II (anaerobic) (11/24 steps found)

Sequence Analysis Tools

See A3Q9G6 at UniProt or InterPro

Protein Sequence (737 amino acids)

>Shew_0242 molydopterin dinucleotide-binding region (RefSeq) (Shewanella loihica PV-4)
MKMNRRTFLQGVGASSVVGSLSGLMPGIASAGEKGGAPDKLLKRQGEIKYHTCQRNCADR
CLLKFTVQNGRMTYVEGASELKKMGTSPCVKGHAYVQYTYAADRILHPMERAGKKGEGKW
RRISWDEAYDKIASRLQQIIKDHGADSILPYSYSGHEGVIGKYGGPSRFFNAVGARKLDR
KVCVFAAYEGLKSVTGTYQGPDPYDNIYTNCYISWGQNETATNVHGIKFINQARDRGAKL
LVVNPVRTPIASQADIWLQPKPSTDTHLATGIMKYLVEHDLADLEFIKANTLGYDQLLER
LNTMSYEEIERVTGVPKAKMFEFARVYGESELSVLRLGYGMQRNYNGARMSRAIAMMHAV
AGQYGKIGNGFIYDNTQADDSLNYSKGRADHIHPNPDTVGHVNMTEIAKALDPENPMAYG
KPIKPIKAVINYNGNFVSVAPDSNACRRGAMRDDLFLVVHDFLMTDTAELADIIVPAATQ
FEFPDMGTDYNCYHMQTSEKVIEPLGESKDNWIFFKELGARMGLDRFPEMRVDYEQILRD
FLDTEEPAFRHNNITYEQIIRDKFVTVYDQRPYFGDGKYKTPSGKIEFYSEMMKEAGYHP
VIDFGLPEDEMVQEEKTLPFRLLSPAIPQRANSSFYNVKYIRNFPAYFAKINAEDAKELG
IQNNDRVRLSNQRGEAHFIAQVSTQVVRGTVMAPKNNWRRMDPQGKDSCTNNLTTDTLTD
MGGCSAYHSTRVAIAKA