Protein Info for Shew_0215 in Shewanella loihica PV-4

Annotation: sporulation domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 transmembrane" amino acids 231 to 252 (22 residues), see Phobius details PF13401: AAA_22" amino acids 26 to 150 (125 residues), 66.3 bits, see alignment E=3.4e-22 PF05036: SPOR" amino acids 422 to 491 (70 residues), 23.9 bits, see alignment E=4.4e-09

Best Hits

KEGG orthology group: K03112, DamX protein (inferred from 100% identity to slo:Shew_0215)

Predicted SEED Role

"DamX, an inner membrane protein involved in bile resistance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9D9 at UniProt or InterPro

Protein Sequence (511 amino acids)

>Shew_0215 sporulation domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MTFQTAILLPSQESLLHRLQHVVLYGQQLTVLTGETGAGKTTLATALVDTLDDVSSALVV
CPQHVDSAEIRRKILVQLLTEPVFDDELPLPETLLRLGDALPSHSHIVLDDAQYLPLELW
AECIVLSQLNIAGKKLSLTLTAPADYLNQILTQLPETQRPLLLPVAISPLTLPEREGLYY
TLLHRSEETPFTPRDIVKDQLQRQQGTPAEVLNLLYLALHGEPAAPKKNPWPVYLVIGAC
MASLLASLYWLWAEPEELMTKSKVQTVAAVRAAAFNTQYGQRLLSAYFEQGSQLRNTLTK
STDAALPATKTKIESGDQIETLTQALPDAQPSSASPRSQSDSQLKEVSEEQRPQAEALTY
QEASEPEVAEQPSQVAGEIEQTQQSQVSDEARAAKPVETFALVPVSEPKESRKLAASQPH
PAGFTLQLATVKRLESLDATIAKLPDVNQVQIARYKSYWVLLYGQYTDRQAGQQAALDLA
QTSQLASPWVRAWVDLSGYELQQGAVSREIH