Protein Info for Shew_0208 in Shewanella loihica PV-4

Annotation: type IV pilus assembly protein PilM (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 transmembrane" amino acids 77 to 94 (18 residues), see Phobius details TIGR01175: type IV pilus assembly protein PilM" amino acids 12 to 353 (342 residues), 314.9 bits, see alignment E=3.1e-98 PF11104: PilM_2" amino acids 15 to 354 (340 residues), 451.8 bits, see alignment E=2e-139 PF14450: FtsA" amino acids 197 to 322 (126 residues), 42.7 bits, see alignment E=1e-14

Best Hits

KEGG orthology group: K02662, type IV pilus assembly protein PilM (inferred from 100% identity to slo:Shew_0208)

Predicted SEED Role

"Type IV pilus biogenesis protein PilM" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9D2 at UniProt or InterPro

Protein Sequence (359 amino acids)

>Shew_0208 type IV pilus assembly protein PilM (RefSeq) (Shewanella loihica PV-4)
MLSNLWKRQAPQMVGIDIGSHEIKAILLSKTADGYKILSHAAVPVKKGAVNDHEIRDSDA
VLESLRLIKRSLPKSVKYAAAAVSGSAVMTKVIYMDASLSEEEMETQIEIEADNLIPYSL
DEVSIDFETLSVNSADPSKVDVLLSACRTENIDARVDSLDDINLEAKVIDVEGYALGRSF
ELVAAQLPDGAEDKVVALVDIGANMTTFAVVEKGETTFIREQAFGGEQFTQSILSFYGMS
HEQAEKAKLEGDLPRNYMFEVLSPFQTQLLQQIKRTLQIYCTSSGKDKVDHIVLCGGTSK
LEGMANLLTNELGVHTIIADPFLGCLHADEQVKTQLQPTINKYMVACGLALRSYSQWRT