Protein Info for Shew_0106 in Shewanella loihica PV-4

Annotation: putative DNA uptake protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 TIGR03341: IscR-regulated protein YhgI" amino acids 2 to 191 (190 residues), 325.7 bits, see alignment E=4.5e-102 PF01521: Fe-S_biosyn" amino acids 2 to 99 (98 residues), 50.2 bits, see alignment E=2.8e-17 PF01106: NifU" amino acids 111 to 174 (64 residues), 72 bits, see alignment E=3.5e-24

Best Hits

Swiss-Prot: 100% identical to NFUA_SHELP: Fe/S biogenesis protein NfuA (nfuA) from Shewanella loihica (strain ATCC BAA-1088 / PV-4)

KEGG orthology group: K07400, Fe/S biogenesis protein NfuA (inferred from 100% identity to slo:Shew_0106)

MetaCyc: 78% identical to iron-sulfur cluster carrier protein NfuA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"NfuA Fe-S protein maturation"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q930 at UniProt or InterPro

Protein Sequence (192 amino acids)

>Shew_0106 putative DNA uptake protein (RefSeq) (Shewanella loihica PV-4)
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTPSAECGVSYCPPDAVEADDIELEFNG
FHAMVDEKSAPFLEDASIDFVTDQLGSQLTLKAPNAKMRKVDADAPLKERIEYVIQSEIN
PQLASHGGNIMLVDIDEAGIAILQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELTGVRD
VTEHQHGEHSYQ