Protein Info for DVUA0009 in Desulfovibrio vulgaris Hildenborough JW710
Name: nifE
Annotation: nitrogenase MoFe cofactor biosynthesis protein NifE domain protein (TIGR)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02587, nitrogenase molybdenum-cofactor synthesis protein NifE (inferred from 100% identity to dvu:DVUA0009)Predicted SEED Role
"Nitrogenase FeMo-cofactor scaffold and assembly protein NifE" in subsystem Nitrogen fixation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q72WT0 at UniProt or InterPro
Protein Sequence (568 amino acids)
>DVUA0009 nitrogenase MoFe cofactor biosynthesis protein NifE domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710) MAPATPPATPPATPPAPASDGLLEERRGQVHRAGQGPIDLACNRESLAGAVSQRACVFCG SRVVLYPIADALHLVHGPVGCAAYTWDIRGALSSGPELHRLSFSTDLGERDIIFGGEPKL EAALDELITRHAPKAAFVYATCIVGLIGDDIGAVCKRVAARHGIPVLPVQSEGFKGNKRE GYEAACAAMFTLTGTGATDGIGPASVNILGDFNLAGELWIIRGYLERMGVQVVANITGDG RVDDLRRCHGAALNLVQCSGATMPLARMMREAYGTPTLRVSYLGIEDMADSLYNVAEHFR EVCPGIVERTRDLVREEIATLMPRLRQLRRDLEGKRAAIYVGGAFKAFSLIKAFRHLGMQ VALVGSQTGTDEDYRELEAICDPGTIIVDDANALELAHFVRTLDVDIFVGGVKERPIAHK LGIGFCDHNHERKIALAGFEGMYNFAREVHASVTSPVWRFTPRSRFPAAARPEGDGHANC PAGDEDADCPERDGHANCPEGDGQADNPADRADRHLGADAPAHERDGHPANPAGDGDADC PANPAGHAPHDLFTEGNATEGGAHHGRP