Protein Info for DVU2499 in Desulfovibrio vulgaris Hildenborough JW710

Name: ftsZ
Annotation: cell division protein FtsZ (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 TIGR00065: cell division protein FtsZ" amino acids 8 to 323 (316 residues), 409.4 bits, see alignment E=7.5e-127 PF00091: Tubulin" amino acids 13 to 172 (160 residues), 160.8 bits, see alignment E=5e-51 PF12327: FtsZ_C" amino acids 222 to 317 (96 residues), 113.8 bits, see alignment E=3.8e-37

Best Hits

Swiss-Prot: 53% identical to FTSZ_KOCRD: Cell division protein FtsZ (ftsZ) from Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)

KEGG orthology group: K03531, cell division protein FtsZ (inferred from 100% identity to dvl:Dvul_0746)

Predicted SEED Role

"Cell division protein FtsZ (EC 3.4.24.-)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728V3 at UniProt or InterPro

Protein Sequence (449 amino acids)

>DVU2499 cell division protein FtsZ (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MEFMDIDIENSAKIKVIGVGGGGGNAVQNMITSTLKGVTFICANTDVQALGRSSAELKIQ
LGEKLTKGLGAGANPQIGRDAAVESMNAIKDCIGEADMVFVTAGMGGGTGTGAAPVIAQA
AREMGALTVGVVTKPFFFEGRKRLEAAEQGIADFREHVDSLITIPNDRLLSLAPKKATFV
EMLKKADEVLYFAVKGISDLIMVPGLINLDFADVKAVMGESGLAMMGAGIARGESRAREA
AMKAITSPLLEDVSIDGARGVLMNITCGPDLTIDEVSEAAGIIQEAAHDEARIFFGTVFD
ESAGDEMRITVIATGIEACGSATVTPNAQNGNIAQFRRPSQQQAAPAAQRPAPQARVESG
PVAEFGRQQPQQAPQQPQQAPQQAQQVAPGRGLSNFSDEDRNIPAYLRKQTRNPSGISRS
NGGHVPGEDDFIFDEDEFELPTFIRKQAD