Protein Info for DVU0645 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: methyl-accepting chemotaxis protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 transmembrane" amino acids 9 to 29 (21 residues), see Phobius details amino acids 287 to 308 (22 residues), see Phobius details PF02743: dCache_1" amino acids 74 to 268 (195 residues), 91.1 bits, see alignment E=1.6e-29 PF17201: Cache_3-Cache_2" amino acids 123 to 284 (162 residues), 46.9 bits, see alignment E=5.1e-16 PF00672: HAMP" amino acids 321 to 355 (35 residues), 32.5 bits, see alignment (E = 1.8e-11) PF00015: MCPsignal" amino acids 460 to 644 (185 residues), 158.8 bits, see alignment E=2.4e-50

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to dvu:DVU0645)

Predicted SEED Role

"methyl-accepting chemotaxis sensory transducer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72ED3 at UniProt or InterPro

Protein Sequence (679 amino acids)

>DVU0645 methyl-accepting chemotaxis protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MRIGIMQKLLLPIIGVVIIGLGTSAWIAYEASSVAVSEALVEQQAIAVDALRRELSGLVD
SCRRDVELDADSYEIMRYFASQDAERESALEAVRRMFESRISRRPLLQTLSLVGPDGAVL
ASNRKDGNAINVSSRDYFRKAMSGEVAISDVFASGIDGNPIFVVAAPVRVSGRIAGVVYS
AVKLQGLSEGAVSRVKVGKRGYAFIADAKGRVLAHPRRDLIMKLDLSTMEWGREMLGKDA
GVVRYLFEGQEKIVAFEREPVTRWMVGVTAEQSDIFDSIVSIRNRSALAAGVVLLCIVGV
GVFVVRGISQALGEGVRFATDVAAGDLSRDINLNRNDELGQLASALTTMVKRLREMIATA
EQKTSEAEAQSLAAQEATRVAEEARRQAEGARREGLLDAAGRLEGIVMRVTSASEQLAAQ
VEQSSRGADLQRERSAEAATAMEEMTATVIEVARNASEASESADKARQQATDGAGVVLSM
VEAIGTVDAQTGELRGSLGTLGERAEGIGQIMTVISDIADQTNLLALNAAIEAARAGDAG
RGFAVVADEVRKLAEKTMNATREVGEAVRAIQNGTRDSIAGMEQASMSVGRSNELAGLAG
AALQRIVTFVEASADQVRSIATASEEQSAASEQISRGTEEVNRIAAETADAMRQSAQAVT
ELAAMAQELQQLIERLKQG