Protein Info for SO4537.2 in Shewanella oneidensis MR-1

Annotation: hypothetical Zn-dependent peptidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00675: Peptidase_M16" amino acids 42 to 156 (115 residues), 85.4 bits, see alignment E=4e-28 PF05193: Peptidase_M16_C" amino acids 194 to 370 (177 residues), 133.7 bits, see alignment E=7.1e-43

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_4537.2)

Predicted SEED Role

"Protease precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See K4PSX9 at UniProt or InterPro

Protein Sequence (443 amino acids)

>SO4537.2 hypothetical Zn-dependent peptidase (NCBI ptt file) (Shewanella oneidensis MR-1)
MKRTLSALVLAMGLLNPLSQAQATTAEDIKSFTLANGMKIMVLEDSSIPNANMYLFWKVG
SRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAEGGANNAYTTEDMTVYTDWFPAN
ALETMFDLEADRIANLDINPEMVESERGVVQSERSTGLENSNWNTLEGEIKGVAFLAHPY
SWSVIGHESDIAAWTLEDLVQYHKTYYAPNNAVVVIAGDVKLAQVKALADKYFAPIPAQT
PPKAIRTVEPEQKGERRTFVQKASVSTPNVMLAYHIPAATHADFYALDLLSSILSQGNSS
RLYQALVDKQVALEAQTYMPMSVDPNLFYVMGVATPEVKASTLERALIEQIDAIATNGVS
QQELDKVKNIKLMDFYRAMETINGKANTIGTYEMYFGSYDKLFNAPEAYNKVTSADIQRV
AQTYLRKSNRTVAVLAANEENSQ