Protein Info for Dshi_4176 in Dinoroseobacter shibae DFL-12

Annotation: oxidoreductase FAD/NAD(P)-binding domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 PF00175: NAD_binding_1" amino acids 106 to 202 (97 residues), 52.2 bits, see alignment E=4.6e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_4176)

Predicted SEED Role

"Ferredoxin reductase" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LUG9 at UniProt or InterPro

Protein Sequence (220 amino acids)

>Dshi_4176 oxidoreductase FAD/NAD(P)-binding domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MTHKITLLETVELTPDTRHYVFTRPEGYGFTPGQATDFALDRYGWRDATRPFTFTGDPEA
DVLCFTIKTYADREGVTDALWSATPGDGALIGDPWGAISDKGPGVFIAGGAGITPFLGIL
KARARAGQLDGATLIFANGGPRDIIFRPLWDSLKGLKTVYAVSEDGAGFAYRRITGEMLE
AEIDDWDQRFYVCGPPPMEEDVVAMLTARGVPEDSIIREA