Protein Info for Dshi_4154 in Dinoroseobacter shibae DFL-12

Annotation: beta-lactamase domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR04558: quinoprotein relay system zinc metallohydrolase 1" amino acids 30 to 313 (284 residues), 395.3 bits, see alignment E=6.8e-123 PF00753: Lactamase_B" amino acids 59 to 241 (183 residues), 88.2 bits, see alignment E=3.6e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_4154)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LUE7 at UniProt or InterPro

Protein Sequence (317 amino acids)

>Dshi_4154 beta-lactamase domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MADLRFSRRASLGLLASAALIRPARAAARLSYDLRPQAVAKGVWMIEGSTEYFTMENGGA
IVNCALLQGDTGLIVVDTGSSLRYGEALKSVADGLDLRGVSTVINTHHHPDHFFGNQVFA
DRPILALGETILQADAQADALADNMYRILGDWMRGTDPVIPRNVISGGDVVIDGRAFLAL
PLSGHTEGDLALLDRESGILIAGDLVFYDRAATTPSADLPVWHAALDTLEGTGAAAVLPG
HGPIDRSGAAIPQTRAYLRWLEDTLRTAAGQGLDMIEVMDLPLPPEFAGLGAEPEEFHRS
IAHLYPSIEREVMPRAN