Protein Info for Dshi_4008 in Dinoroseobacter shibae DFL-12

Annotation: putative methylase/helicase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 836 PF13872: AAA_34" amino acids 390 to 717 (328 residues), 384.8 bits, see alignment E=1.2e-119

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_4008)

Predicted SEED Role

"FIG01027258: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LU27 at UniProt or InterPro

Protein Sequence (836 amino acids)

>Dshi_4008 putative methylase/helicase (RefSeq) (Dinoroseobacter shibae DFL-12)
MAKPKTANPTFSISDAALISALAQIGQEVDHQPLRSSALARIMRETFHGSDAGGVWEWRM
AYDLKQAAAIQVLLRGDGAACDIATAKLLASRLLTETRRSEQQIRLQQFSTPLPFAAMAV
RAAAIRKGETVLEPSAGTGALAAFAARAGATLLLNEIDPFRQSLLRAVFGGDVTGHDGEH
IDDLLQTPVLPDVVVMNPPFASSVDRSRDKHIAAKHLIAAAKRLAPGGRLVAIMPPGFTP
ERDTAHWSRACGLLTPRLALTMPGQVYRKLGTSVETQLMVFDKVQEDGEMIRASVRDLDE
ALPFVDAVAATRPEMRPVQRAVAIPHGRPTVPSSAPRKTAAAPVAASKPQANAVVQLSIK
SLEAPRDNTPVSDIYARYRPQRIEIADAQEHPTPLVESIAMASVAPPEPSGAAGSELRLP
ARLIKEGHLSEAQLETIIMANDAHGRNLPGRFTIDDDQTKLTRADDDPDARAYRLGYFLG
DGTGCGKGRECAGLILVNWLAGRRKAIWVSKSATLIEDAIRDWIDLGGSPADIQPLSKWK
PDQPIPMGDGILFVTYATLRSAGKCGTTRLSQILDWMGEDFDGVLAFDEAHAMQNAAGSE
QGRGVKPSQQGLAGLRLQLAAPRARVFYISATGATSVHNLAYAARLGLWGQGPEYPFPSR
ESFVSAMEAGGVAAMEVVARDLKTLGLYTARALSFDGVEYDVLEHALTPAQIEIYDAYAG
AFRTIHHNLEAALTATGVNDASGETNASAARASAKSRFESTKQRFFNHLLMGMKAPSIIR
AIEDDLATGHACVIQVVSTGESLLKRRLETMDAEDELVEGALTPRDYVLSKALDNT