Protein Info for Dshi_3904 in Dinoroseobacter shibae DFL-12

Annotation: SSS sodium solute transporter superfamily (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 526 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 67 (24 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 125 to 148 (24 residues), see Phobius details amino acids 160 to 177 (18 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 236 to 254 (19 residues), see Phobius details amino acids 275 to 299 (25 residues), see Phobius details amino acids 313 to 336 (24 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 398 to 420 (23 residues), see Phobius details amino acids 427 to 447 (21 residues), see Phobius details amino acids 454 to 475 (22 residues), see Phobius details amino acids 507 to 525 (19 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 41 to 435 (395 residues), 304.7 bits, see alignment E=5.6e-95 PF00474: SSF" amino acids 42 to 435 (394 residues), 231.1 bits, see alignment E=1.1e-72

Best Hits

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 100% identity to dsh:Dshi_3904)

Predicted SEED Role

"sodium/glucose cotransporter 2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LTR5 at UniProt or InterPro

Protein Sequence (526 amino acids)

>Dshi_3904 SSS sodium solute transporter superfamily (RefSeq) (Dinoroseobacter shibae DFL-12)
MEQQIDANLTMLDYGVIAVYLAIVIAIGVWVARKTRTGEDLFLAGRSLGWAAIGFSLFAS
NISTSTLVGLTGSAYTGGLTVSSYEWMAGIPLLFMAFIFAPVFLKSRISTTPEYLENRYS
RRVRLYFSGLTIVFTVIVDTAGGLYAGAVVLKVFFPDLDIWMSCVAIGLFAGIYTATGGL
RAVVYTDILQAVVLICGTGLTAFLMYQSVDFSWESVRSQVPEGHLSIVQPIDDDTLPWPG
LFTGVWLLGFWYWVTNQYIVQRVLGAKDLSNAQWGAILGGILKILPTFFIILPGVMALVT
LPDIQNSDQVFPIIITEVLPSGLTGLVMAGLIAAIMSTVDSTLNSSSTLLINDFLTRPEK
EPDPETAKKWGMMATLGFMVIAIAWAPLIQYFGGLWAYIQQAFSVLVPPLVVCFTLGALW
SRGTENAAFWTLIIGHTLGLVVFMLNQFGIWPLHYTISVTIMTAVSAAIFVALSLRDDTP
DVREDALWQRADAFDTPATTAPVLKNVKTHAILLILLMIGTLVLFW