Protein Info for Dshi_3857 in Dinoroseobacter shibae DFL-12

Annotation: polysaccharide biosynthesis protein CapD (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 119 to 145 (27 residues), see Phobius details PF13727: CoA_binding_3" amino acids 119 to 243 (125 residues), 27.9 bits, see alignment E=7.7e-10 PF02719: Polysacc_synt_2" amino acids 291 to 581 (291 residues), 375.9 bits, see alignment E=4.5e-116 PF04321: RmlD_sub_bind" amino acids 291 to 484 (194 residues), 43.3 bits, see alignment E=8.7e-15 PF01370: Epimerase" amino acids 291 to 511 (221 residues), 74.6 bits, see alignment E=2.9e-24 PF16363: GDP_Man_Dehyd" amino acids 292 to 417 (126 residues), 40.8 bits, see alignment E=7.2e-14 PF01073: 3Beta_HSD" amino acids 292 to 422 (131 residues), 27.9 bits, see alignment E=4.4e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3857)

Predicted SEED Role

"UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-)" in subsystem N-linked Glycosylation in Bacteria (EC 4.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.-

Use Curated BLAST to search for 4.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LTL8 at UniProt or InterPro

Protein Sequence (630 amino acids)

>Dshi_3857 polysaccharide biosynthesis protein CapD (RefSeq) (Dinoroseobacter shibae DFL-12)
MNGLGCSVLNFVKSLTLGQKAITLLVVDLVLIPLALIVTFALQPIPVSPGETIALILPIL
PYLLAASALVAFWLGIPYIRLNAYEARAVGKTAQYAAANGLIALVLSKIAGLGLTTGLYV
IFAGCFFLFSAASRVVMLQILTAIYRRDEGHTRVMIYGAGTTGTQLVSALNAHKTIYPVA
FVDDNAALHGLTVAGLPVHSPVRIRELVRDKQIDRVLLAVPSLSQPKQAQLARRLQKLGL
EVQALPSFSQLIGEEELVDKLKPVESHTFLGRQQVCTELERGCESYADRVVLISGAGGSI
GSELCRQVLACRPAKLVLYELNELALYNVDMELRSLAEVTGTELVPVLGSVTDPRQVRGV
LAEHKVQVVLHAAAYKHVPLVEANPLAGLANNVFGTQTLAREAAEYGIERFILISSDKAV
RPTNVMGASKRLAELVIQDLETRYTGTVFTMVRFGNVLGSSGSVVPLFQEQIRRGGPVTV
TDPKVTRYFMTVQEAVRLVLTAGSMARGGEVFVLDMGAPVPIVQLARQVIESAGYTVRDD
ATPDGDIEIVFTGLRPGEKMFEELTITDDHIGTRHPKLFCAREQSLSEIEIAGILRSLRQ
AVASGDPDAGRAVITRWVEGYVPGVKSVPL