Protein Info for Dshi_3687 in Dinoroseobacter shibae DFL-12

Annotation: cobalt transport protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 44 to 63 (20 residues), see Phobius details amino acids 69 to 106 (38 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details PF02361: CbiQ" amino acids 10 to 194 (185 residues), 62.5 bits, see alignment E=2.3e-21

Best Hits

KEGG orthology group: K02008, cobalt/nickel transport system permease protein (inferred from 100% identity to dsh:Dshi_3687)

Predicted SEED Role

"Transmembrane component BioN of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LT53 at UniProt or InterPro

Protein Sequence (197 amino acids)

>Dshi_3687 cobalt transport protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MIVDLYVFGNSPLHRLSPGYKILALVLFCTLLFVLPGWVPLVGGAILVAIGCWLAGIGFS
HAYQAIRPALWILAVIFIAQVILTGLELAAFVVVRFGILIIAASVITMTTKTSEFVDGIQ
AGLRHAPSWVPADHIALAISLALRFIPLVRTTLDEVRMAQKARGLDRSVKALLVPLVVRT
LKTGDEIAEAIQARSPL