Protein Info for Dshi_3402 in Dinoroseobacter shibae DFL-12

Annotation: Serralysin (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 PF10462: Peptidase_M66" amino acids 153 to 187 (35 residues), 22.1 bits, see alignment 1.7e-08 PF13583: Reprolysin_4" amino acids 159 to 218 (60 residues), 28.5 bits, see alignment E=3e-10 PF08548: Peptidase_M10_C" amino acids 240 to 408 (169 residues), 66.3 bits, see alignment E=8.8e-22 PF00353: HemolysinCabind" amino acids 326 to 354 (29 residues), 22 bits, see alignment (E = 3.2e-08) amino acids 355 to 379 (25 residues), 15.9 bits, see alignment (E = 2.6e-06)

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3402)

Predicted SEED Role

"Neutral zinc metallopeptidase( EC:3.4.24.- )"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LNP1 at UniProt or InterPro

Protein Sequence (451 amino acids)

>Dshi_3402 Serralysin (RefSeq) (Dinoroseobacter shibae DFL-12)
MCTICQSMNPNRDRFDYHEAPFPSLFSGDRIAANLPTFTVDQVADQLKSGFFKSREASWD
VEPGGEAIDVDISRLTEKGQFYAELALDAWTMTTGIEFNITELEIFAFGFTRSGIIFDDT
DSGAYAQPIVNSENEIYTARINISQDWIRNDGETIDNYSFQTFIHEIGHALGLEHAGNYN
GNAKYSTDALYTNDSWQMSIMSYFSQTDNASIDASFAYVVTPMIADITAVQQLYGVAGDL
RPGNTIYGQPTTQGGSLMSMADGYYEDFGDTSRPITYTIIDDGGFDAINFSDVTADQNIN
LNGGAVSDVNGLKGNLVIFSTTVIEYVVSGSGNDTLTGNGANNHFFAGDGRDTIFGGDGD
DILEGQGGIDILTGGAGRDGFVLSGTGFDGLDIVTDFTDGEDLLFFAAADSFSDISVSER
ATGTVVGFNGEFAILLGVSSNQISADDFVFG