Protein Info for Dshi_3379 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF1078 domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 TIGR03506: flagellar hook-basal body protein" amino acids 6 to 415 (410 residues), 253.3 bits, see alignment E=2.9e-79 PF00460: Flg_bb_rod" amino acids 7 to 37 (31 residues), 36.3 bits, see alignment (E = 4.2e-13) PF06429: Flg_bbr_C" amino acids 390 to 432 (43 residues), 54.2 bits, see alignment 8.1e-19

Best Hits

KEGG orthology group: K02390, flagellar hook protein FlgE (inferred from 100% identity to dsh:Dshi_3379)

Predicted SEED Role

"Flagellar hook protein FlgE" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LNL8 at UniProt or InterPro

Protein Sequence (434 amino acids)

>Dshi_3379 protein of unknown function DUF1078 domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MTISSSLNAGVSGLNANATRLATISDNIANSSTYGYKRAEADFQSLVINGNSSGTYSAGG
VRVTTTRVIDEQGPLVTTSNPTDLAVGGSGMLPVTTLSALDENTGGYPLSLMTTGSFSPN
ADGVLTTETGMVLMGWPAAPDGTVPEFPRDTVDGLEPITVNLNQFAGDPTTRIDLGVNLP
ASETEAGSSGDSIDLSIEYFGNLGTSETLGVTYTPQVPASGASNTWTMTITDSASGGAVV
GEYELTFDDSRGAGGTLASVTAVSGGPFDPVQGTVEITADGGPVTVKIGSVGDENGMTQL
SDTFAPVSISKNGSPVGNLSTVEVDPNGFVVAVYDTGFTRTIYQVPLADVPNPNGLLSRD
NQSYMISPESGPFFLWNAGEGPTGDVIGFALEESAADVAGELTRLITTQRAYSSNAKIIQ
TVDEMLQETTNIKR