Protein Info for Dshi_3375 in Dinoroseobacter shibae DFL-12

Annotation: SMC domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF02463: SMC_N" amino acids 6 to 333 (328 residues), 68.2 bits, see alignment E=1.1e-22 PF13476: AAA_23" amino acids 8 to 50 (43 residues), 29.7 bits, see alignment 1.5e-10

Best Hits

KEGG orthology group: K03629, DNA replication and repair protein RecF (inferred from 100% identity to dsh:Dshi_3375)

Predicted SEED Role

"DNA recombination and repair protein RecF" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LNL4 at UniProt or InterPro

Protein Sequence (361 amino acids)

>Dshi_3375 SMC domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MTGVAVTSLSLSHFRSHTHLTLSLDERPVVLHGPNGIGKTNVLEALSFLSPGRGLRRAKT
EAVGQSEAGLGWRVSALVKSGGREREVMTRSDAGASRTVQLDGKPVPQMALAELVPMVWL
VPAMDRLWIEAAEGRRKFLDRMTLNFVTTHGRDVLAYERAMRDRNRLLKDGVRDPHWYHA
LEAQMAEAGARITQNRQRCLSEIEAAQADATTAFPFAGLQIEAHDGRAPLRTKGEIENTL
RCNRYMDQTAGRTLDGPHRDDLAAVYVSKGTPARDCSTGEQKALLISLILSMSRAVKSLV
GQAPLVLLDEVAAHLDQERQRALYDEICALGAQAWMTGTGAELFQPLGERAQFIALPLDG
T