Protein Info for Dshi_3297 in Dinoroseobacter shibae DFL-12

Annotation: histone deacetylase superfamily (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 PF00850: Hist_deacetyl" amino acids 20 to 308 (289 residues), 285 bits, see alignment E=3.8e-89

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3297)

Predicted SEED Role

"Acetylspermidine deacetylase (EC 3.5.1.48); Deacetylases, including yeast histone deacetylase and acetoin utilization protein" (EC 3.5.1.48)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LMV5 at UniProt or InterPro

Protein Sequence (313 amino acids)

>Dshi_3297 histone deacetylase superfamily (RefSeq) (Dinoroseobacter shibae DFL-12)
MSTAVYTHSECLSHVTPPGHPEQVARLVAVAEALDTPGFAALERRSAPLGEIADILRCHP
QGYVDRVRAAIPEEGAGVVSLDADTHVMSGSWNAALRGVGGVCAAVDAVLAGEVGNAFVA
CRPPGHHAETETAMGFCLFGNIAIGAKRALDHHGLSRVAVVDFDVHHGNGTQDLLWDEAR
AFFISSHQMPLYPGSGARHETGAHGNVFNLPFPPDTAGPAFRRQYEAEVFPALENFRPEL
ILVSAGFDAHRADPLAQMALVEEDFAWVTGRLCEIAAEFCDGRVVSTLEGGYDLPALGAS
TAAHVKTLMEHAQ