Protein Info for Dshi_3269 in Dinoroseobacter shibae DFL-12

Annotation: L-carnitine dehydratase/bile acid-inducible protein F (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 43% identical to SUCHY_RAT: Succinate--hydroxymethylglutarate CoA-transferase (Sugct) from Rattus norvegicus

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3269)

MetaCyc: 59% identical to succinate--lglutarate CoA-transferase (Agrobacterium fabrum C58)
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

oxalate degradation II (1/3 steps found)
L-lysine degradation X (3/6 steps found)
L-lysine degradation IV (2/5 steps found)
superpathway of L-lysine degradation (9/43 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.3.13 or 2.8.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LMS7 at UniProt or InterPro

Protein Sequence (368 amino acids)

>Dshi_3269 L-carnitine dehydratase/bile acid-inducible protein F (RefSeq) (Dinoroseobacter shibae DFL-12)
MTPLEGLKVVELARILAGPWIGQALADLGAEVIKVEAPQGDDTRTWGPPFITRDGDRSAA
YFYAANRGKRSVVADFRTEAGQAKVRDLVADADILIENFKVGGLAKYGLDYAALAAINPR
LIYCSVTGFGQDGPYAHRAGYDFMIQGMSGLMSITGEPDAAPQKVGVAVTDIVTGLYGTI
GILAAVEQRHRTGRGQHLDMALLDCATALLANQAMNQLATGTAPTRLGNAHPNIVPYQVF
EAADGHMILAVGNDGQFASLCEILDLPGTASDPRFATNAGRVENRDALTELLSLRLRGWS
VAQLLSALEAAGVPAGPINTIDQVFADPQVQARGLQVSVEGVPGVRGPWRFSDAELSLDR
TAPKLPDP