Protein Info for Dshi_3176 in Dinoroseobacter shibae DFL-12

Annotation: putative transcriptional regulator, AsnC family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 PF13404: HTH_AsnC-type" amino acids 8 to 48 (41 residues), 31.8 bits, see alignment 1e-11 PF17805: AsnC_trans_reg2" amino acids 68 to 133 (66 residues), 46.9 bits, see alignment E=2.5e-16 amino acids 230 to 317 (88 residues), 83.6 bits, see alignment E=8.6e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3176)

Predicted SEED Role

"Heme d1 biosynthesis protein NirD / Heme d1 biosynthesis protein NirL" in subsystem Dissimilatory nitrite reductase or Heme biosynthesis orphans

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LM00 at UniProt or InterPro

Protein Sequence (331 amino acids)

>Dshi_3176 putative transcriptional regulator, AsnC family (RefSeq) (Dinoroseobacter shibae DFL-12)
MTLAEISLDDRLLNEFQRNVPVVARPFAEIAKSVGTTEDTVLARMQALVARGAVTRFGAT
CRPNTAGASTLAAVSAPEWEVEKTAAIINAQPGVNHSYLREHRWNIWFVATGPDRAHVDA
ALAQIGAETGLRVLDLRLVAPFNIDLGFDMSGKAAHGVEPSRVATLGAIDATDRKLMQVL
STGLPMVARPFRAVAPVCDLDEAGALRRAARLLEEGYLTRFGVIVRHRALGWRANAMVVW
QVPPAQVAQAGPALAAVPGVTLCYQRKAVPGVWPYTLYNMIHGRSREDAMAVLKRARALP
ELRGVPHEILFSLRCFKQTGALIDLPRKEPA