Protein Info for Dshi_3018 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF1523 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 150 to 170 (21 residues), see Phobius details PF07509: DUF1523" amino acids 6 to 176 (171 residues), 240.2 bits, see alignment E=4.6e-76

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3018)

Predicted SEED Role

"FIG01031270: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LKG8 at UniProt or InterPro

Protein Sequence (217 amino acids)

>Dshi_3018 protein of unknown function DUF1523 (RefSeq) (Dinoroseobacter shibae DFL-12)
MFWTYLRWTLKLTLLVLIGGLLHYVLPQHDVVRIVDAYERRIDFTDNNRIFWAQPDSGAP
VADNRDVRFIDAVRPNGKQIVYRNEDTNWSWPFYFKFDSSDLNAAAKDLVSTAEEPTWVI
IRHYGWRSNFFSIFPNAVHLTVTDTPDPRIIPWFNIAFFLVLALIGLRIWRWWVNFHEDR
IEPLVDDVVIAMHRAEDKADRTGGRIARWWDRVRGRA