Protein Info for Dshi_2869 in Dinoroseobacter shibae DFL-12

Annotation: Gluconate 2-dehydrogenase (acceptor) (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13442: Cytochrome_CBB3" amino acids 39 to 142 (104 residues), 24 bits, see alignment E=4.1e-09 PF00034: Cytochrom_C" amino acids 40 to 145 (106 residues), 40.4 bits, see alignment E=6.3e-14 amino acids 196 to 288 (93 residues), 23.8 bits, see alignment E=9.7e-09

Best Hits

Swiss-Prot: 58% identical to CYCG_RHOS4: Diheme cytochrome c-type (cycG) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_2869)

Predicted SEED Role

"Putative diheme cytochrome c-553" in subsystem Soluble cytochromes and functionally related electron carriers

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LJJ9 at UniProt or InterPro

Protein Sequence (292 amino acids)

>Dshi_2869 Gluconate 2-dehydrogenase (acceptor) (RefSeq) (Dinoroseobacter shibae DFL-12)
MKRFLAFAGLLLAAGVSLGLFFTRAVPVPEERFAALTGDAEAGEAVFHAAGCASCHAAPG
ASGEARLVLAGGQRFASPFGTFVAPNISPHPEVGIGDWSQADFASAVLAGVAPDGSHYYP
AFPYTAYALMEDQDVADLWAYMQGLPETDTPNAPHELGFPFNIRRSVGAWKLLSPMPDWV
GPEVPGDGRYLVEALAHCAECHTPRDGLGRLDRARWMAGAPNPSGKGRIPGITPAQLDWS
AGDIAYYLETGFTPDFDSAGGHMASVITNMAQLTAADREAIAAYVKALQPAE