Protein Info for Dshi_2651 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF152 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF02578: Cu-oxidase_4" amino acids 18 to 250 (233 residues), 247.2 bits, see alignment E=7.9e-78 TIGR00726: YfiH family protein" amino acids 29 to 236 (208 residues), 172.3 bits, see alignment E=4.7e-55

Best Hits

KEGG orthology group: K05810, conserved hypothetical protein (inferred from 100% identity to dsh:Dshi_2651)

Predicted SEED Role

"COG1496: Uncharacterized conserved protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LI50 at UniProt or InterPro

Protein Sequence (252 amino acids)

>Dshi_2651 protein of unknown function DUF152 (RefSeq) (Dinoroseobacter shibae DFL-12)
MTLEILTSPALPVAHGFFTRKGGASSGVFEGLNCGPGSSDQSDTVALNRARVAAAMEVPV
SALATVNQVHSPDVVTLEAAPAPGPKPTADAMVTATPGLVLGILTADCQPVLFADGQAGV
IGAAHAGWRGALDGVLEATIDAMVAAGARREAITAVIGPSISQRAYEVGPEFLDRFLDDD
PENSRFFAGGQDGRAHFDLISYGLTRLRGAGIAQAEWTGHCTYSDPGRFFSYRRSVHGGE
ADYGRLISTIRL