Protein Info for Dshi_2430 in Dinoroseobacter shibae DFL-12

Annotation: L-rhamnose 1-epimerase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05336: rhaM
  • amino acids 11 to 111 (101 residues), 102.2 bits, E=8.9e-34
• TIGR02625: L-rhamnose mutarotase
  • amino acids 12 to 111 (100 residues), 105.2 bits, E=1e-34

Best Hits

Swiss-Prot: 100% identical to RHAM_DINSH: L-rhamnose mutarotase (rhaM) from Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)

KEGG orthology group: K03534, L-rhamnose mutarotase [EC: 5.1.3.-] (inferred from 100% identity to dsh:Dshi_2430)

MetaCyc: 69% identical to L-rhamnose mutarotase monomer (Rhizobium leguminosarum bv. trifolii)
RXN0-5306 [EC: 5.1.3.32]

Predicted SEED Role

"L-rhamnose mutarotase" in subsystem L-rhamnose utilization

MetaCyc Pathways

• L-rhamnose degradation I (5/5 steps found)
• superpathway of fucose and rhamnose degradation (8/12 steps found)

KEGG Metabolic Maps

• Nucleotide sugars metabolism
• Polyketide sugar unit biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.- or 5.1.3.32

Sequence Analysis Tools

See A8LS71 at UniProt or InterPro

Protein Sequence (112 amino acids)

>Dshi_2430 L-rhamnose 1-epimerase (RefSeq) (Dinoroseobacter shibae DFL-12)
MVHVAGALMEKIAFKMMLNPGCREEYIKRHDAIWPELVDLLRKAGVSDYSIHLDPETDTL
FAVLWRKEGHGMDDLPSHPVMQKWWAHMADIMQTQPDNAPVVTPLDTVFHMP