Protein Info for Dshi_2377 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF839 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 674 transmembrane" amino acids 52 to 67 (16 residues), see Phobius details PF05787: PhoX" amino acids 85 to 625 (541 residues), 531.5 bits, see alignment E=1.7e-163

Best Hits

KEGG orthology group: K07093, (no description) (inferred from 100% identity to dsh:Dshi_2377)

Predicted SEED Role

"Putative phosphatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LRT2 at UniProt or InterPro

Protein Sequence (674 amino acids)

>Dshi_2377 protein of unknown function DUF839 (RefSeq) (Dinoroseobacter shibae DFL-12)
MARDEIIHDPEYGNKAEAFEAYDDIPTNPNLGNTIGDVINERYGRREVLRGMLGVSATTA
LFGSSALVAPKRAAAMTAADSRYVFDELAWGNDERHHIADGYNADVLVRWGDPITADAPE
FDVMNQTPEAQSKQFGYNNDYVGFAEIEPGRGMLCVNHEYTNEEVMFPGLGRQDRTGFEG
MTKELVDIEMAAHGGSVFEVVKGADGKWSVNRDNPANRRVTANTPMTIDGPAAGHPRMRT
SADPAGMTVLGTINNCAGGMTPWGTYLMAEENFHGYFWSDTLDAEGRPDVSAQPEADSMI
RYGVPGRWYAWGKFHDRFNIDKEPNESNRFGYIVEVDPMNPDAMPIKHTALGRFRHEGAE
TTIASDGRLVIYSGDDNRFDYLYKWVSADPVTEENSRFGSELLSEGTLYVARFNPDGVID
WLPLVHGEGPLTAENGFESQADIAIDTRLAADALGATPMDRPEDAQPGPNGTAYVMLTNN
NRRTPEQVNAANPRPESNFGHIIEIREDGGNHSSPKGTWEILVLCGDPAIAEVGARWNPE
TSEAGWFSSPDNCAIDDAGRLWVSTDQGSGWGRTGKSDGLYSLETEGDLRGHAKLFFRCP
VGGELCGPYFADNDETLFLAVQHPGTDGTKDYPGFERDSTFEDPATRWPDFDPNMPPRPS
VVVVTKQGGGKIAV