Protein Info for Dshi_2238 in Dinoroseobacter shibae DFL-12

Annotation: transcriptional regulator, LacI family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 PF00356: LacI" amino acids 10 to 52 (43 residues), 52.8 bits, see alignment 5.3e-18 PF00532: Peripla_BP_1" amino acids 65 to 278 (214 residues), 87.9 bits, see alignment E=1.7e-28 PF13407: Peripla_BP_4" amino acids 66 to 277 (212 residues), 73.5 bits, see alignment E=4.2e-24 PF13377: Peripla_BP_3" amino acids 173 to 331 (159 residues), 102.4 bits, see alignment E=5.9e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_2238)

Predicted SEED Role

"Maltose operon transcriptional repressor MalR, LacI family" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LR51 at UniProt or InterPro

Protein Sequence (344 amino acids)

>Dshi_2238 transcriptional regulator, LacI family (RefSeq) (Dinoroseobacter shibae DFL-12)
MARDRVTSLDVARVAGVSQSAVSRVFTPGASVSPKTAKKVRAAAEELGYRPNVLARSLIT
GQSKIIGLVVAYLDNQFYPDALERLSMALQDRGYHILVFMASGTGAQVDRVIGELLDYQV
DGIITASVGMSDELTKRCNSAGIPVVMFNRGQDDARLSSVTSDNFTGAREIARFLAAGGH
ERIAHITGWTGSSTGRDRKAGFLAGLEDAGLAAHGIVDGHYRRAEAQAAAHALFAGAAPP
DAIFVGNDHMAFAVMDTVRGELGVRIPEDVSIVGYDDVPLADWGAYRLTTWRQPSNRMVA
ATVELLLGLIDDADRAPEKLEIAGRLIVRDSARVPADWSENARV