Protein Info for Dshi_2230 in Dinoroseobacter shibae DFL-12

Annotation: polyhydroxyalkonate synthesis repressor, PhaR (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 PF07879: PHB_acc_N" amino acids 9 to 69 (61 residues), 93.3 bits, see alignment E=7.7e-31 TIGR01848: polyhydroxyalkanoate synthesis repressor PhaR" amino acids 9 to 113 (105 residues), 152 bits, see alignment E=3.4e-49 PF05233: PHB_acc" amino acids 73 to 111 (39 residues), 41 bits, see alignment 1.7e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_2230)

Predicted SEED Role

"PhbF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LR43 at UniProt or InterPro

Protein Sequence (186 amino acids)

>Dshi_2230 polyhydroxyalkonate synthesis repressor, PhaR (RefSeq) (Dinoroseobacter shibae DFL-12)
MAETGKPLLIKRYASRRLYNTETSDYVTLEDIAKFIREGREVQIVDLKSGDNLTRQYLLQ
IIAEHESRGENVLPISVLTDLVRSYAGQSTSVVPQFLAASFEMLRDSQEKMINNLGGMPN
PMVAVPGFEQMQKQQKAFLETMMGGWTPSSTMPTEEASEKPEDSTADIDDIKRQLADLQK
KLSGLN