Protein Info for Dshi_2200 in Dinoroseobacter shibae DFL-12

Annotation: regulatory protein TetR (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF00440: TetR_N" amino acids 15 to 61 (47 residues), 25 bits, see alignment E=1.3e-09 PF17935: TetR_C_27" amino acids 83 to 183 (101 residues), 50.2 bits, see alignment E=2.4e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_2200)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LR13 at UniProt or InterPro

Protein Sequence (196 amino acids)

>Dshi_2200 regulatory protein TetR (RefSeq) (Dinoroseobacter shibae DFL-12)
MARPKPDTDKIRSRLIAEAEAQLEETDGRRLVLSDLAERVGMSQSHVHTFFPTKADLIRE
LAARWFDAVETASADAASADAPPDARLEQWVLSILRIKRDRFDANPKLFRAYLELAGAHM
DLVQSHAAALRADLARILRDLVGAQDADHAVPLVENATLLFRTPQNIAAYRARATDEAAR
AICHLLTRSLARSKGT