Protein Info for Dshi_2125 in Dinoroseobacter shibae DFL-12

Annotation: transcriptional regulator, LysR family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 PF00126: HTH_1" amino acids 11 to 69 (59 residues), 57.8 bits, see alignment E=8.7e-20 PF03466: LysR_substrate" amino acids 96 to 283 (188 residues), 74.6 bits, see alignment E=7.6e-25

Best Hits

Swiss-Prot: 34% identical to PECT_DICD3: HTH-type transcriptional regulator PecT (pecT) from Dickeya dadantii (strain 3937)

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_2125)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LQJ4 at UniProt or InterPro

Protein Sequence (298 amino acids)

>Dshi_2125 transcriptional regulator, LysR family (RefSeq) (Dinoroseobacter shibae DFL-12)
MARKFTNLQTDLLRTFVTVVDLRNYTETGRILGRTQPAISLQIKRLEEITGKKLLAQQGK
QVELTPDGQTLLGYAREMLRLNDRAVANLQQASILGTLRVGLPVDYAIEYFQSIITRFAR
ENPAVQLDIRCNRSPDLLSALHVDDLDMTIAITDSMPAPHVSVYWSEHPVWVCARDHRID
PDQPLKVVAHPNGCFYRKRMIDALNTEGRDWRISFESLGVSALQKAVLDGMGVTALTKKT
LLPGMRLLSPGEGFPNLANIHVGLFYKHVKMSDAALKLIEKITEDVSTFRLPTRARTK