Protein Info for Dshi_1976 in Dinoroseobacter shibae DFL-12

Annotation: PfkB domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 5 to 296 (292 residues), 214.7 bits, E=1.9e-67
• PF08543: Phos_pyr_kin
  • amino acids 160 to 275 (116 residues), 48.5 bits, E=8.2e-17

Best Hits

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 100% identity to dsh:Dshi_1976)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15

Sequence Analysis Tools

See A8LP33 at UniProt or InterPro

Protein Sequence (305 amino acids)

>Dshi_1976 PfkB domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MGKPIVILGIFVADCAFRAARPPRMGETVLGDSFALNPGGKGSNQAIAAAKSGGDARFLT
RLGEDAFADMAAAIWAEAGVRATAPRDPASYTGAAYIYVDPATGDNAIIVAPGAAALLGP
ADLDAQAEMIGGAGVFLTQLEQPMPAARRGLEIARAAGVTTILNPAPAAPLDDALLALCD
IVTPNETEAEALTGHPVTGPDDAVRAADALLARGPGAVIVTLGAQGVLYRSATQTIHQPA
FTPGPVVETTGAGDAFNGALATALAEGQDTASALRFGCATASISVTRPGAGPSMPSRAEI
DALLA