Protein Info for Dshi_1703 in Dinoroseobacter shibae DFL-12

Annotation: putative ferric uptake regulator, Fur family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 PF01475: FUR" amino acids 34 to 150 (117 residues), 28.3 bits, see alignment E=8.8e-11

Best Hits

KEGG orthology group: K09823, Fur family transcriptional regulator, zinc uptake regulator (inferred from 100% identity to dsh:Dshi_1703)

Predicted SEED Role

"Zinc uptake regulation protein ZUR" in subsystem Oxidative stress or Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LLR7 at UniProt or InterPro

Protein Sequence (165 amino acids)

>Dshi_1703 putative ferric uptake regulator, Fur family (RefSeq) (Dinoroseobacter shibae DFL-12)
MSAENAAPIGFEKHDHGACVSQALAAAEARCAAEGLRLTPVRRKVLELLLREHRALGAYA
ILDLLREAGFGSQPPVAYRALDFLSEHGFVHKIERLNAFVACAHPTERHSPAFMICRLCD
AVAEAQSPPSRGALGAAAKAAGFQIEKTVVEAEGLCPACIEKADA