Protein Info for Dshi_1357 in Dinoroseobacter shibae DFL-12

Annotation: ABC transporter related (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 110.7 bits, see alignment E=1.4e-35 PF08402: TOBE_2" amino acids 270 to 341 (72 residues), 57.8 bits, see alignment E=1.4e-19

Best Hits

Swiss-Prot: 56% identical to MALK_PHOPR: Maltose/maltodextrin import ATP-binding protein MalK (malK) from Photobacterium profundum (strain SS9)

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 100% identity to dsh:Dshi_1357)

Predicted SEED Role

"Various polyols ABC transporter, ATP-binding component" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LIY5 at UniProt or InterPro

Protein Sequence (349 amino acids)

>Dshi_1357 ABC transporter related (RefSeq) (Dinoroseobacter shibae DFL-12)
MGAITLSKVEKWFGDVQVIKGVDLEIRDGEFVVFVGPSGCGKSTLLRMIGGLEDTSRGAM
LIDGVDVTDHPPAKRGLTMVFQSYALYPHMSVRENMGFSLKTAGAPAAEIAEKVEAAAAV
LKLEPYLDRRPKDLSGGQRQRVAIGRSIVRAPTAFLFDEPLSNLDAALRVEMRYEIAKLH
QSLDTTMIYVTHDQVEAMTLADRIVVLEFGKIAQVGTPRELYETPANLFVAQFIGSPKMN
VMPCTTDAGRYRLSAGRGGVFSGDRPAVQLGIRPEHITPGAPGTGACDGRVDVVEYLGAD
TLLVLDCGPEGRVTVRVIGDTDLTPGDAVGLSFNPDRLSFFDTDGLAIR