Protein Info for Dshi_1201 in Dinoroseobacter shibae DFL-12

Annotation: Tetratricopeptide TPR_2 repeat protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07719: TPR_2" amino acids 102 to 135 (34 residues), 24.9 bits, see alignment 4.6e-09 PF14559: TPR_19" amino acids 114 to 167 (54 residues), 26.9 bits, see alignment E=1.5e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_1201)

Predicted SEED Role

"TPR domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LI89 at UniProt or InterPro

Protein Sequence (183 amino acids)

>Dshi_1201 Tetratricopeptide TPR_2 repeat protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MRHGLLALVLAMGLPATGWAEGCAPVPDTRAEIAGLHAQLQAAPSETAARPLIGALWQVW
TRAPDAAAQALLDEGMRKRREYDFAGAVEVFDALIAYCPDYAEGWNQRAFARFLQDRYDA
ALGDLDRALALSPTHTAALSGKALTLIRMGRMGLAQDVLRAAVALNPWLPERVYLLRPPG
REL