Protein Info for Dshi_1200 in Dinoroseobacter shibae DFL-12

Annotation: Rhomboid family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 transmembrane" amino acids 14 to 34 (21 residues), see Phobius details amino acids 65 to 88 (24 residues), see Phobius details amino acids 100 to 118 (19 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 151 to 176 (26 residues), see Phobius details amino acids 191 to 212 (22 residues), see Phobius details PF01694: Rhomboid" amino acids 62 to 211 (150 residues), 118.4 bits, see alignment E=1.4e-38

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_1200)

Predicted SEED Role

"FIG056164: rhomboid family serine protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LI88 at UniProt or InterPro

Protein Sequence (258 amino acids)

>Dshi_1200 Rhomboid family protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MFPIRDHNPSERTPYVTLMLIGLNVLIFLAYLPLMGDPRALSLFFQTWGLVPRELTAGSG
TLGLFTSMFLHGGFMHLAGNMLFLWVFGDNLEDRLGHGRFLGFYLLCGIGAALAQVLAAP
FSPVPMVGASGAIAGVLGGYLLLYPKARVDVLIIIVIIFRVIPIPAGLVLSGWFALQVFS
GASTPMDGGGVAYWAHAGGFVAGLILILPVWLRLGGPRFWARTDGHPDHPEARYDAIASR
IPKVRRRTSRVPRVRRRK