Protein Info for Dshi_0776 in Dinoroseobacter shibae DFL-12

Annotation: cobalamin B12-binding domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 261 PF02310: B12-binding" amino acids 143 to 255 (113 residues), 43.8 bits, see alignment E=1.1e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0776)

Predicted SEED Role

"PpaA, heme-binding SCHIC domain sensory protein, regulator for photosystem formation" in subsystem Oxygen and light sensor PpaA-PpsR

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LQX8 at UniProt or InterPro

Protein Sequence (261 amino acids)

>Dshi_0776 cobalamin B12-binding domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MPASDDAEPRKTETETETGIGASPSEDTLMTVVKLALENVATRVARPEVPASEDFIESLC
TLLVARDIEASEAMVRSRIGQRQGYADLADGIFAACARRLGTRWEEDRLSFADVAIAVTE
LHRLHQRVGRRYVPLIRKADESHAVFATLPRQTHTFGIILAAEAFRQAGWQVDLQLEMLP
KEIVDRIRRLRPDAVGLTASKFDPVQPLRLLIGQIQKLPFNVPILLGGAGAADLHGTLQP
GTPVQVVHDIDSALRAVQTAG