Protein Info for Dshi_0555 in Dinoroseobacter shibae DFL-12

Annotation: FGGY-family pentulose kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 transmembrane" amino acids 472 to 490 (19 residues), see Phobius details TIGR01315: FGGY-family pentulose kinase" amino acids 4 to 533 (530 residues), 646.8 bits, see alignment E=1.5e-198 PF00370: FGGY_N" amino acids 4 to 261 (258 residues), 105 bits, see alignment E=5.2e-34 PF02782: FGGY_C" amino acids 275 to 484 (210 residues), 162.8 bits, see alignment E=9.3e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0555)

Predicted SEED Role

"D-ribulokinase (EC 2.7.1.47)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization (EC 2.7.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LPH8 at UniProt or InterPro

Protein Sequence (544 amino acids)

>Dshi_0555 FGGY-family pentulose kinase (RefSeq) (Dinoroseobacter shibae DFL-12)
MTCFIGVDVGTGSARAGVFDLEGTLLASRKHDIQMWRALGNIAEQSSDDIWQAVCSCVRG
AISDAGISPQEVRGIGFDAACSLVALDGDMRPLSVSASGDVARNVIVWMDQRATDQAARI
NAKEYPVLEFVGGAISPEMQTPKLLWLRENMPESFAAAGQFFDLVDYLTWAATGSLARSC
CTVTCKWTYLAHEDRWDNSYFEEIGLRELASENFSRIGTEIVPPGSALAQGLSHGAAAQM
GLLAGIPVAAGLIDAHAGGIGTVGADPERGPEATMAYVFGTSACTMSTSPEAHRVPGVWG
PYYSAMVPGMWLSEGGQSAAGEAIAHLVTVHPASAEAEAAARAEGLSLQTYLLRQVDRRV
SEKSEVALLAGARVVVPDFLGNRAPFADPGATGAILGLTLSADFEDLLATYVAAVLGVGY
GLRQIMQAQGQHGVRPSTIVVSGGAGESDTIKQLLADSSGFPVLSTRSAEPVLLGAAMLG
AVAAGAYPTIQSAMSAMSSVKARFDPSSAEILALHQKRFEAFEMLQKADQTVRQAMVALP
KGSV