Protein Info for Dshi_0456 in Dinoroseobacter shibae DFL-12

Annotation: ATPase associated with various cellular activities AAA_3 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 PF20030: bpMoxR" amino acids 15 to 177 (163 residues), 55.4 bits, see alignment E=9.3e-19 PF07726: AAA_3" amino acids 42 to 172 (131 residues), 205.1 bits, see alignment E=6.5e-65 PF07728: AAA_5" amino acids 42 to 170 (129 residues), 52.5 bits, see alignment E=1.1e-17 PF17863: AAA_lid_2" amino acids 244 to 311 (68 residues), 69.1 bits, see alignment E=4.6e-23

Best Hits

KEGG orthology group: K03924, MoxR-like ATPase [EC: 3.6.3.-] (inferred from 100% identity to dsh:Dshi_0456)

Predicted SEED Role

"MoxR-like ATPase in aerotolerance operon"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LNP6 at UniProt or InterPro

Protein Sequence (318 amino acids)

>Dshi_0456 ATPase associated with various cellular activities AAA_3 (RefSeq) (Dinoroseobacter shibae DFL-12)
MDTRPTPGDRGVAALSAHLAAGLVGHERLIESLLVALLADGHLLIEGAPGLAKTRAVKWL
ADAVDGSFARIQCTPDLMPSDVTGTPVYKPQDGAFEFVRGPVFNNLVLVDEINRAPPKVQ
SALLEAMAEHQVTAGVETYRLPEPFLVVATQNPIEHDGTFPLPEAQLDRFLLHTVLELPG
IETERRILELVEAETQAGVAPTLSLSLEALNAARAKVRAIHLAPELRDYIVRLVMATREG
PLSEDVEHAVSPRGTLAMAAAARARAFLHGRDYALPEDVDELAGDALAHRMVLSWRAVAD
GRKPRDVVRDILTAVEPL