Protein Info for Dshi_0435 in Dinoroseobacter shibae DFL-12

Annotation: ATP synthase F1, beta subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 TIGR01039: ATP synthase F1, beta subunit" amino acids 10 to 460 (451 residues), 594.9 bits, see alignment E=5.5e-183 PF02874: ATP-synt_ab_N" amino acids 13 to 74 (62 residues), 22.8 bits, see alignment E=1.1e-08 PF00006: ATP-synt_ab" amino acids 132 to 345 (214 residues), 242.5 bits, see alignment E=3.8e-76

Best Hits

Swiss-Prot: 100% identical to ATPB1_DINSH: ATP synthase subunit beta 1 (atpD1) from Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)

KEGG orthology group: K02112, F-type H+-transporting ATPase subunit beta [EC: 3.6.3.14] (inferred from 100% identity to dsh:Dshi_0435)

MetaCyc: 54% identical to F1 beta chain (Mycoplasmoides pneumoniae M129)

Predicted SEED Role

"ATP synthase beta chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LN39 at UniProt or InterPro

Protein Sequence (462 amino acids)

>Dshi_0435 ATP synthase F1, beta subunit (RefSeq) (Dinoroseobacter shibae DFL-12)
MPADPEVHFEGTIVAIRGGVVDVAFAEAVPRIHALIVAGGVAMEVASIVGEGVVRCIALG
PTRGLGLGTRATGTRAGIEVPVGEGVLGRMLDMFGAPLDGAPPPEATARRPIHRPPPVLS
DRVLRAEVLETGIKAIDLLSPIERGGKTGLFGGAGVGKTVLLSELIHNTVEHHHGVSLFC
GIGERSREAEELWREMGEAGVRERMVMLFGQMNEAPGVRFLVGHSALTMAEYFRDDREQD
VLLLIDNIFRFVQAGSEVSGLLGRMPSRVGYQPTLATELAALQERIASTRRGAITSIQAV
YVPADDFTDPAAAHIFSHLSASVVLSRKRASEGLYPAVDPLASTSVMLTPEVVGQRHYDI
ARGVRRTLAEYEDLRDIIAMLGIEELSAHDRAVVARARRLERFLTQPFFTVGAAAGTLGK
LVPIAETLDGCEEILSQTSFERPESAYYMIGALSDLRKEAAA