Protein Info for Dshi_0249 in Dinoroseobacter shibae DFL-12

Annotation: acriflavin resistance protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 194 transmembrane" amino acids 17 to 36 (20 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 69 to 92 (24 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details amino acids 145 to 168 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 8 to 170 (163 residues), 56.2 bits, see alignment E=2.1e-19 PF03176: MMPL" amino acids 21 to 172 (152 residues), 31.6 bits, see alignment E=1.3e-11 PF02355: SecD_SecF" amino acids 22 to 169 (148 residues), 31 bits, see alignment E=2.4e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0249)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LLI8 at UniProt or InterPro

Protein Sequence (194 amino acids)

>Dshi_0249 acriflavin resistance protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MALGGDADARNDTVNRLLAPLGLIVTLSLATIVLTFGSFRLAAVTLVVAVLSAGLSLLSL
AVFQYPFGITAIIGVIGSIGVSINAAIIILTGLQQDEAAAAGDRDAMAQVVMNGSRHILS
TTLTTFGGFLPLILAGGGFWPPFAMAVAGGVLLSTVVSFYFTPPLFALVRPRRTKAANQV
EGHTCLAELKIAAE