Protein Info for Dshi_0180 in Dinoroseobacter shibae DFL-12
Annotation: peptide deformylase (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 40% identical to DEF_BRASB: Peptide deformylase (def) from Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
KEGG orthology group: K01462, peptide deformylase [EC: 3.5.1.88] (inferred from 100% identity to dsh:Dshi_0180)MetaCyc: 38% identical to peptide deformylase (Escherichia coli K-12 substr. MG1655)
Peptide deformylase. [EC: 3.5.1.88]
Predicted SEED Role
"Peptide deformylase (EC 3.5.1.88)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase (EC 3.5.1.88)
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.88
Use Curated BLAST to search for 3.5.1.88
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A8LLB9 at UniProt or InterPro
Protein Sequence (168 amino acids)
>Dshi_0180 peptide deformylase (RefSeq) (Dinoroseobacter shibae DFL-12) MIRPFLSWPDARLRTPAAPVAEITDEIRTVWDDMIDTMEAMPGMGPGAGLAAPQIGVMQA LAVVDASEERGRAIRMANPQVLHASAQLRSHEEASPNLPGVFAKIDRPRAVTVRFLDANG AVKEQDFVGLWATSVQHQIDHLAGRMYFDRLSKTKRDMLLRKARKLAR