Protein Info for Dshi_0163 in Dinoroseobacter shibae DFL-12

Annotation: chromosome segregation protein SMC (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1150 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1142 (1141 residues), 822.6 bits, see alignment E=3e-251 PF02463: SMC_N" amino acids 4 to 1135 (1132 residues), 192.5 bits, see alignment E=1.1e-60 PF13476: AAA_23" amino acids 5 to 210 (206 residues), 53.6 bits, see alignment E=7.1e-18 PF13304: AAA_21" amino acids 26 to 102 (77 residues), 28.3 bits, see alignment 2.5e-10

Best Hits

KEGG orthology group: K03529, chromosome segregation protein (inferred from 100% identity to dsh:Dshi_0163)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LKR9 at UniProt or InterPro

Protein Sequence (1150 amino acids)

>Dshi_0163 chromosome segregation protein SMC (RefSeq) (Dinoroseobacter shibae DFL-12)
MRFTRLRLNGFKSFVDPTDLIIGDGLTGVVGPNGCGKSNLLEALRWVMGENRPTAMRGGG
MEDVIFAGAASRPARNFAEVALILDNSDRRAPAGFNDTDQLEIIRRITRDVGSAYKTNGK
DVRARDVQMLFADASTGAHSPALVRQGQISELINAKPKARRRILEEAAGISGLYQRRHEA
ELKLRGAETNLDRVDDVLEALAAQLATLARQAKQAARYREIGAQLRRAEGLLLYRRWREA
DETRLVAVGELTARTTEAAAAETAARQAAKARVAADEALPPLREEEAIAGAVVQRLHVQR
DTLADQETRAREAIETLTGRIATLEADIAREEELNRDAGETIAKLDWEQAQIAKASVGHD
EKLAAAAEAAQAASEVLTDRETTQSEMTEDVARLAARHQSTQRLLQEAGRAETRAQEQVG
RAEAALSEAQAGLCDAETRFVAAERDQQAAQGETEAAEAALAAAEAERSEVQGAEAEARA
ARSEAEGEATALRAEVGALEKLVDRARAEGGQVLDAVTAAPGYEAALGAALADDLKAPEV
EGDRSGWHLLPGYDAAQKLPDGAAPLSAHVEVPAVLARRMAQVGLVDRAEGARLQPALKP
GQRLVSREGDLWRWDGLAARAEDAPSAAAARLQQINRLAALKADLEAAEAKAATARATHE
GLQAAMRAATEADRAAREARKGAERALGEASRALSRAEADRNIMAGKLETLGSAVSRYRD
EVLEARKAVAEAQAAQADLGDLEAARAQVEAVRVTVDAARMTMLAKRSAHDELRREGEAR
TRRSQEITTQISGWRHRLETAEAHKGELEGRLEASRAELKSATAAPEEIAAKRDALAHEI
ARAEARKAAAADALSTAEGAARSAEQAERDAERAASEAREARARAEARAEAAAETVTLAA
ERIQEALEVTPQQLLDTLKVGPDAMPASDAIEAEVNRLKRQREAMGAVNLRAEEDAKAVE
EEYDGLVAEKGDLEGAIGKLRTGISSLNKEGRERLLTAFEQVNDNFAMLFTHLFGGGEAK
LVLVESDDPLEAGLEIMCQPPGKRLSTLSLLSGGEQTLTALALIFAVFLANPAPICVLDE
VDAPLDDANVTRFCDLLDEMTRRTETRFLIITHHAVTMARMDRLFGVTMGEQGVSQLVSV
DLRKAESLVA