Protein Info for BT4717 in Bacteroides thetaiotaomicron VPI-5482

Annotation: integral membrane protein, putative permease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 36 to 53 (18 residues), see Phobius details amino acids 66 to 86 (21 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 213 to 237 (25 residues), see Phobius details amino acids 249 to 266 (18 residues), see Phobius details amino acids 272 to 291 (20 residues), see Phobius details PF00892: EamA" amino acids 3 to 137 (135 residues), 72.1 bits, see alignment E=2.6e-24 amino acids 152 to 289 (138 residues), 49.1 bits, see alignment E=3.4e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4717)

Predicted SEED Role

"Transporter, EamA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89YL4 at UniProt or InterPro

Protein Sequence (310 amino acids)

>BT4717 integral membrane protein, putative permease (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKKGLFYAILASVLWAIVNPFIKQGLSYDFSPMNFAGIRFTTVGIILFAYTWHKGMWKEI
RQHSKLFLNLILINMFMGYTAFYFGVDFVSGAISSIIMGMTPLINVLLAHLLASNDRLNV
HKIISLIVSLIGLLLIVGMGSNGAPLDWKGITGIVLLLLSIIFQGYSAISVSEDKGKINP
IFLNAVQMFFGGLLIYMIGLGTEGYHSFIGKPAGFYISLSILVFISVFAFSFWFIALQSK
GAKVSDINMCRLINPILGAILSWIMLPGEYPTFSTVAGMIIIVSSLIIYFKGAEIGRWLK
RHTAGSSTQE