Protein Info for BT4639 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein, putative membrane protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 66 to 89 (24 residues), see Phobius details amino acids 128 to 138 (11 residues), see Phobius details amino acids 151 to 175 (25 residues), see Phobius details amino acids 187 to 205 (19 residues), see Phobius details PF09335: SNARE_assoc" amino acids 46 to 173 (128 residues), 86.6 bits, see alignment E=9.7e-29

Best Hits

Swiss-Prot: 65% identical to DEDA_ECOLI: Protein DedA (dedA) from Escherichia coli (strain K12)

KEGG orthology group: K03975, membrane-associated protein (inferred from 100% identity to bth:BT_4639)

Predicted SEED Role

"DedA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89YU2 at UniProt or InterPro

Protein Sequence (213 amino acids)

>BT4639 conserved hypothetical protein, putative membrane protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MEFILDFILHIDQYMINIVQDYHTWAYAILFIIIFCETGLVVTPFLPGDSLLFVAGAISA
LPGMPIDIHILVLILFAAAVLGDSCNYMIGHFFGRKLFHNPNSRIFKQSYLDKTHEFYKK
YGGKTIILARFVPIVRTFAPFIAGMGKMHYYYFMIYNLIGGAIWVVLFCYAGYFFGDLPF
VQENLKLLIIAIIFISILPAIIEILRAKLGSKQ