Protein Info for BT4465 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein, putative outer membrane protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 31 to 91 (61 residues), 36.6 bits, see alignment 1.7e-12 PF13715: CarbopepD_reg_2" amino acids 31 to 111 (81 residues), 55.4 bits, see alignment E=1.8e-18 PF12450: vWF_A" amino acids 144 to 236 (93 residues), 134.1 bits, see alignment E=4.9e-43 PF13768: VWA_3" amino acids 253 to 409 (157 residues), 35.8 bits, see alignment E=2.9e-12 PF00092: VWA" amino acids 253 to 414 (162 residues), 68.2 bits, see alignment E=3.8e-22 PF13519: VWA_2" amino acids 254 to 358 (105 residues), 66.4 bits, see alignment E=1.2e-21 PF12034: YfbK_C" amino acids 429 to 612 (184 residues), 252 bits, see alignment E=1.4e-78

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 100% identity to bth:BT_4465)

Predicted SEED Role

"Von Willebrand factor type A domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89ZB2 at UniProt or InterPro

Protein Sequence (621 amino acids)

>BT4465 conserved hypothetical protein, putative outer membrane protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKTNQLRAMMLTVMLVITTLGGTVWAQPLIVKGTVTDGSDGSPLVGCAVTVKGTSRGAVT
NLQGQYRIEANKGETLIFSYIGFDKVEKVVFSAKMDVSLKASSDVLEECVVVGYGSQRKV
AVTGAISTVNLASLRHPSVRMDAVNTEEYKSISENGFKQVGESPLSTFSIDVDAASYSNM
RRMINSGTLPVPDAIRTEELVNYFSYDYAKPTGSDPVKITMEAGVCPWNADHRLVRIGLK
AREIPTDKLPESNLVFLIDVSGSMWGPTRLDLVKSSLKLLVNNLREKDKVAIVVYAGNAS
VKLESTPGSDKQKIRDAIDELTSGGSTAGGAGIQLAYKVAKQNFLPKGNNRIILCSDGDF
NVGVSSVEGLEQLIEKERKSGVFLSVLGYGMGNYKDNKGQALAEKGNGNHAYIDNLQEAN
RVLVGEFGATLHTVAKDVKLQVEFNPAQVQAYRLVGYESRLLKDEDFNNDAKDAGELGAG
HTVTAFYEVIPVGVKNDYVGKIDDLKYQKKQKETVQPTGSNELLTVKLRYKAPDKDVSKK
MEVPFVDNKGNNVSSDFRFASAVAMFGQLLRDSDFKGEASYDKVIGLAKQGLDNDEKGYR
REFIRLVETAKGMKQEKTISD